AS,
Aerosolized substance P may help your throat and lungs recover.
Granted, its highly experimental, but I don't think that's stopped you before
I remember coming across this research a while back and thought this may be good to have in the event of a bird flu pandemic.
Anyway, substance P is a neuropeptide that is involved in many biological functions including among other things, pain signal transmission. Imagine their surprise when these researchers discovered that aerosolized substance P counteracted lung damage caused by jet fuel (contains benzene too).
As I recall from their research, any major trama to the throat and lungs results in depletion of substance P which takes a long time to replace and the lung tissue and immune system suffers as a result.
This research has been followed up and it turns out that aerosolized substance P can prevent lung toxicity from many sources including cigarette smoke.
Substance P can be purchased from Sigma Co., for "research purposes only."
You might also considered breathing treatments with H2 gas (2%) and consumption of H2 saturated water (see US Patent 20070148256 "Pharmacologic-functioning water and usage of the same").
Protection from JP-8 jet fuel induced immunotoxicity by administration of aerosolized substance P.
Toxicol Ind Health. 1997 Sep-Oct;13(5):571-88.
Harris DT, Sakiestewa D, Robledo RF, Witten M.
Department of Microbiology and Immunology University of Arizona, Tucson 85721, USA.
davidh@aruba.ccit.arizona.edu
Chronic exposure to jet fuel has been shown to cause human liver dysfunction, emotional dysfunction, abnormal electroencephalograms, shortened attention spans, and decreased sensorimotor speed. The United States Air Force has decided to implement the widespread use of JP-8 jet fuel in its operations, although a thorough understanding of its potential effects upon exposed personnel is unclear. Exposure to potential environment toxicants such as JP-8 may have significant effects on host physiology. Previous studies in mice have shown that short-term, low concentration JP-8 exposure had significant effects on the immune system; e.g., decreased viable immune cell numbers, decreased immune organ weights, and loss on immune function that persisted for extended periods of time (i.e., up to 4 weeks post-exposure). Previous studies have shown that JP-8 induced pulmonary dysfunction was associated with a decrease in levels of the neuropeptide substance P (SP) in lung lavage fluids. It was found that administration of aerosolized SP was able to protect exposed animals from such JP-8 induced pulmonary changes. In the current study, aerosolized SP was analyzed for its effects on JP-i induced immunotoxicity in exposed mice. It was observed that SP administration could protect JP-8 exposed animals from losses of viable immune cell numbers, but not losses in immune organ weights. Further, exposure of animals to SP inhibitors generally increased the immunotoxicity of JP-8 exposure. SP appeared to act on all immune cell populations equally as analyzed by flow cytometry, as no one immune cell population appeared to be preferentially protected by SP. Also, SP administration was capable of protecting JP-8 exposed animals from loss of immune function at all concentrations of JP-8 utilized (250-2500 mg/m3). Significantly, SP only needed to be administered for 15 minutes after JP-8 exposure, and was active at both 1 microM and 1 nM concentrations. Thus, SP administration appears to be a relatively simple and efficient means to reverse the immunotoxicity due to hydrocarbon exposure.
“I shall not commit the fashionable stupidity of regarding everything I cannot explain as fraud.â€